WebMouse ATAC-seq data were aligned and filtered based on the mm9 reference genome and analyzed with the same pipeline and tools as human Omni-ATAC ... J. E. J. Rasko, CTCF and BORIS in genome regulation and cancer. Curr. Opin. Genet. Dev. 24, 8–15 (2014). Crossref. PubMed. Google Scholar. 49. R. Brignall et al., Integration of kinase and ...
CUT&Tag profiling of the CTCF DNA-binding protein. a …
We performed genome-wide functional annotation using the experimental design shown in Fig. 1a. Briefly, six epigenetic data types were profiled in eight tissues (liver, lung, spleen, skeletal muscle, subcutaneous adipose, cerebellum, brain cortex, and hypothalamus) collected from sexually mature male chickens, pigs, … See more The data generated allowed the discovery of co-occurring histone modifications, CTCF binding, chromatin accessibility, and gene expression, … See more The data generated in this study represents an important resource for comparative analysis as it provides a set of epigenomic assays from the same tissues at the same … See more Previous comparative studies from ENCODE and modENCODE have shown that while some properties of gene regulation are highly conserved, the specific sequence and genomic position of functional REs are … See more WebAt a specific CTCF binding site on chromosome 1, we observed a clear footprint (a deep notch of ATAC-seq signal), similar to footprints seen by DNase-seq 25,26 , at the precise location of the ... highly influential synonym
Identification of transcription factor binding sites using …
WebFeb 17, 2024 · CTCF-binding, ATAC-seq signal and LTR repeats were enriched at genes escaping XCI when compared to genes subject to XCI; however, enrichment was only observed in three or four of the species tested. LINE and DNA repeats showed enrichment around subject genes, but again not in a consistent subset of species. WebNov 16, 2024 · If a heatmap shows similar signal between ATAC and CUTAC at CTCF sites associated with K3me2/3, but only ATAC shows signal at CTCF sites not associated with these marks, then it implies a degree of specificity for open chromatin near the primary antibody as would be expected from the author's model. 2) Selecting which open … WebFeb 24, 2024 · It was not surprising that CTCF was the most closely matched transcription factor for the significant ATAC-seq peak on the enhancer, along with BORIS, FOXM1, ERα, and the pioneer factor FOXA1 ... small relationship tattoos