Ctgf lncrna
WebJun 8, 2024 · BackgroundChronic liver fibrosis is an inevitable stage for the development of patients with chronic hepatitis B (CHB). However, anti-fibrotic therapies have been … WebDec 1, 2024 · Furthermore, the interaction between lncRNA and TGF-β are paid more attention, and the potential therapy targets are mentioned. Hepatocellular carcinoma (HCC) is a type of liver cancer with poor prognosis. ... Furthermore, TGFβ1 secreted by HPCs can also activate autonomous secretion of connective tissue growth factor (CTGF) …
Ctgf lncrna
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WebA further mechanistic study has revealed that LINC00667 promotes renal fibrosis by regulating the miR-19b-3p/LINC00667/CTGF signaling pathway (Chen et al., 2024). lncRNA TapSAKI is reported as a biomarker with … WebApr 3, 2024 · One of the key mechanisms of cardiac diseases has recently been identified as long non-coding RNA (lncRNA) dysregulation. Through in vitro and in vivo studies, …
WebJan 25, 2024 · Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions, known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the heart muscle. Transforming growth factor β (TGF-β) as a pivotal cytokine/growth factor stimulates fibroblasts and hastens ECM production in injured … WebNov 1, 2024 · In summary, this experiment confirmed the role of lncRNA H19 as a ceRNA in KGN cells, which regulated the expression of CTGF through the lncRNA H19/miR-19b/CTGF regulatory axis, and Anally played an important role in the pathogenesis of PCOS. However, it should be noted that the ceRNA regulatory network is complex (21,22).
WebDec 12, 2024 · During the proliferative phase of diabetic wound healing, lncRNA H19 recruits the transcription factor SRF to the CTGF promoter region, activating CTGF and its downstream MAPK signaling pathway to accelerate fibroblast proliferation and wound healing. These findings elaborate lncRNA H19 as a regulator in the regenerative phase … WebOct 7, 2024 · Finally, luciferase reporter assays showed that the 3'-end sequences of lncRNA H19 and CTGF contained the binding site of miR-19b. In conclusion, our study …
WebJul 18, 2024 · Gene expression data analysis identified several genes, including Il6, Tgfb2, Cxcl1, Mmp13, Ctgf, Sost and lncRNA MALAT1, differentially regulated in co-cultures compared to monocultures. We also identified Sost as a regulator of MALAT1 in PC3 cells.
WebSep 1, 2024 · Download Citation LncRNA TUG1 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR‐133b in Myocardial Fibrosis after Myocardial Infarction Myocardial fibrosis is one ... new single touch payrollWebCCN (for CYR61/ CTGF /NOV) proteins were identified originally from diverse cellular contexts and studied for their growth-promoting activities. It is now known that there are six CCN proteins in mammals. All are short (281–380aa) polypeptides that include four major domains, except for CCN5 that lacks a cysteine knot domain (Fig. 1).CCNs have several … microwave cavity resonanceWebMar 9, 2024 · LncRNA TUG1 acts as a competing endogenous RNA to mediate CTGF expression by sponging miR-133b in myocardial fibrosis after myocardial infarction. ... Connective tissue growth factor (CTGF) has been found to be an important downstream mediator of TGF-beta1, and controls pro-fibrotic activities in renal fibrosis. ... new single wide house trailersWebMay 5, 2024 · This has been supported by expression of specific protein-coding genes that facilitate organ-specific metastatic tropism (such as connective tissue growth factor … microwave cbb61WebMay 13, 2024 · LncRNA myocardial infarction associated transcript (MIAT) aberrant expression has been identified in a number of diseases, ... Connective tissue growth factor (CTGF), a downstream effector of TGF-β2, has been reported to be associated with several cellular functions, ... microwave cavity transmission lorentzianWebDec 30, 2024 · The relative expression levels of lncRNA PVT1, CTGF, E-cadherin and vimentin were analyzed using reverse transfection-quantitative polymerase chain … microwave c bandWebJun 21, 2024 · A lncRNA known as lncRNA megacluster ( lnc-MGC) was found to play a key role in the pathogenesis of early DN ( 72 ). Lnc-MGC is a host gene for miR-379 cluster, i. e., harbors miRNAs in its exonic and intronic sequences and these non-coding RNAs are present within one of the largest miRNA clusters in the genome. microwave cavity paint