Web25 Mar 2024 · Published customer image: . Mouse anti Human aggrecan antibody, clone 7E1 (MCA1451G) used for the detection of aggrecan expressing cells in murine … WebThe large chondroitin sulphated proteoglycan aggrecan (ACAN) is and most plenty non-collagenous protein in cartilage and is essential for its structure also function. Mutations inside ACAN result within a broad phenotypic rainbow of non-lethal skeletal dysplasias contains spondyloepimetaphyseal dysplasia, spondyloepiphyseal dysplasia, familial …
Regulatory activities of the 5
Web14 Feb 2003 · There are currently 30 ADAM genes and 18 ADAMTS genes known in humans . ADAMs are type I transmembrane proteins with extracellularly located N … WebSample type: Serum, plasma and cell culture supernates: Cross reacts with: Mouse: Product overview : The ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked hucks orleans in
Frontiers Description of the molecular and phenotypic spectrum …
Web14 Feb 2003 · Aggrecan core protein has three globular domains (G1, G2 and G3). The N-terminal G1 domain interacts with hyaluronan with the help of a link protein. G1-VDIPEN 341 and G1-NITEGE 373 are G1-bearing N-terminal products generated by MMPs and aggrecanases, respectively. WebVersican (VCAN) is a large extracellular matrix proteoglycan that is expressed in majority human tissues. VCAN is localized on human chromosome 5q14.3, covering a genomic sequence of 109.4 kb. 8 VCAN cDNA contains 15 exons and codes a protein with a molecular mass of >1000 kDa, which belongs to the aggrecan/versican proteoglycan … Aggrecan (ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded by the ACAN gene. This gene is a member of the lectican (chondroitin sulfate proteoglycan) family. The encoded protein is an integral … See more Aggrecan is a high molecular weight (1x10 < M < 3x10 ) proteoglycan. It exhibits a bottlebrush structure, in which chondroitin sulfate and keratan sulfate glycosaminoglycan (GAG) chains are attached to an … See more Aggrecan is a critical component for cartilage structure and the function of joints. Functionally, the … See more • Watanabe H, Yamada Y, Kimata K (1998). "Roles of aggrecan, a large chondroitin sulfate proteoglycan, in cartilage structure and function". J. Biochem. 124 (4): 687–93. doi:10.1093/oxfordjournals.jbchem.a022166. PMID See more The synthesis and degradation of aggrecan are being investigated for their roles in cartilage deterioration during joint injury, disease, and … See more • Aggrecan at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Human ACAN genome location and See more hucks orchard south charleston ohio